The Clinical Imaging Scientist/Physician will provide scientific and clinical input to all aspects of late stage product development. This includes the design, delivery, and interpretation of pivotal clinical trials and of studies that further characterize the overall benefit, risk, and value of late stage development products in the respiratory and immunology therapeutic area. The Clinical Imaging Scientist/Physician also needs to possess strong analytical skills, as you will be responsible for the quality of processes and outcomes related to Imaging endpoints. An important aspect is to be comfortable analyzing large amounts of data, to be able to identify potential data quality issues, as well as opportunities for novel analyses.
The role will have a focus on the integration of clinical imaging in late stage clinical trials and provide strategic and technical expertise on the conception and implementation of imaging endpoints which are to be included in later phases of clinical development (Phase II-III). This includes literature research and frequent interaction with internal and external key experts.
This role will also support consistent implementation of standardized imaging protocols across development programs, including training the wider clinical team. Where there is a new requirement for imaging data collection, you will work with the drug project team, internal/external key experts and imaging CROs to ensure optimal image data collection and analysis.
We are seeking a highly motivated, interactive, and creative person that possesses the ability to work across a highly matrixed environment to advance clinical drug development programs throughout the clinical development process. You will collaborate with colleagues within late stage development Respiratory & Immunology and early stage development groups.
You will work as a member of a diverse and motivated team of researchers spanning across multiple divisions and geographies within Biopharmaceuticals R&D. Clear written and verbal communication skills, as well as capability to present scientific designs and results to multidisciplinary teams and key stakeholders are required. You will work both independently and collaboratively and contribute significantly to study design, regulatory submissions, process improvements, and mentoring.
Key activities and leadership areas
Provide scientific leadership in the innovative design, execution, and interpretation of clinical trials
Be the lead medical imaging scientist/physician in a number of drug projects across the respiratory and immunology portfolio
Provide technical support to develop, implement and maintain standardized imaging protocols
Provide imaging expert input to the design, implementation and reporting of clinical studies with imaging-based end-points, including support for protocol authoring, and regulatory documents/defense
Technical input related to imaging provided to study teams may include site selection, site training, monitor training, logistics, data collection and problem solving
Provide technical input in imaging charter development, radiology manuals, site initiation, data collection, interpretation and reporting, working closely with the study teams and imaging CROs
Act as an imaging subject matter expert to help raise the level of understanding of imaging end points within clinical development - this may include imaging training & education as required
Effectively collaborate with colleagues in other functions including early and late stage Clinical Development, Biometrics, Clinical Operations, PatientSafety, Regulatory Affairs and Medical Affairs
Lead and participate in activities that ensure quality, consistency, and integration of clinical study related deliverables
Present protocol, scientific results, and other key information to multidisciplinary teams and key stakeholders, including presenting at investigator meetings
Will require International and domestic travel
Basic Qualifications
MD with imaging related specialist diploma (radiologist), and/or imaging related scientific doctoral degree (PhD), or other professional training related to clinical imaging, or science related degree with practical experience related to clinical imaging modalities (CT, MRI, PET, SPECT)
Practical experience from working with quantitative image analysis in a clinical and/or academic research setting, with an understanding of image acquisition and reconstruction protocols
Proven ability to work collaboratively in a cross-functional setting
Minium of 3 years of experience in the pharmaceutical industry.
Preferred Qualifications
For MD, at least 3 years clinical experience from a specialist position
Knowledge and experience in lung function and other physiological assessments is desired
Experience of supporting clinical trials, in particular Phase II and Phase III, preferably with an imaging component
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
At AstraZeneca, we are dedicated to being a Great Place to Work. Our team is inclusive and diverse, working in a solution-oriented, trusting, and collaborative work environment. We are committed to improving healthcare and quality of life for patients across a wide range of diseases and disorders by developing innovative therapies. Join us in the Biopharmaceuticals R&D department and contribute to our growing pipeline!
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
