Scientist III at American Cybersystems, Inc. in Lansdale, Pennsylvania

Job Description:

Job Description: The Department of Neuroscience is seeking a bioanalytical scientist to join the MRL Discovery organization in West Point, PA. • In this position, you will be responsible for developing mass spectrometry-based assays for use in preclinical drug development with a focus on neurodegenerative diseases with high unmet medical needs. • Appointees will work within multidisciplinary teams focused on the discovery of novel drug targets and development of biomarkers for clinical translation supporting new therapeutics. • Applicants should have expertise in development of quantitative mass spectrometry assays to support follow-on validation of discovery data for biomarker development. If you are driven and open to learning in a team environment, come join our team.

Responsibilities: The Department of Neuroscience is seeking a bioanalytical scientist to join the MRL Discovery organization in West Point, PA. • In this position, you will be responsible for developing mass spectrometry-based assays for use in preclinical drug development with a focus on neurodegenerative diseases with high unmet medical needs. • Appointees will work within multidisciplinary teams focused on the discovery of novel drug targets and development of biomarkers for clinical translation supporting new therapeutics. • Applicants should have expertise in development of quantitative mass spectrometry assays to support follow-on validation of discovery data for biomarker development. If you are driven and open to learning in a team environment, come join our team.

Qualifications: Job Title: Scientist III, Mass Spectrometry/Analyst, Discovery Neuroscience. Education requirements • PhD with industry or academic experience or Master's with at least 2-3 years of industry experience. Experience/skills required: • Hands-on experience in the development and technical validation of quantitative LC-MS/MS assays using MRM/PRM acquisition • Experience in data analyses covering relative to absolute quantification • Expertise in sample processing and prefractionation across cell, tissue and fluid specimens • Experienced in using automated liquid handling platforms • Experience working collaboratively within cross-functional teams • Self-motivated and resourceful with a demonstrated ability to generate robust and reproducible data in a timely manner • Well-developed oral and written communication skills Desired Competencies (Preferred / not required): • Hands-on experience performing unbiased, quantitative discovery analyses with high resolution LC-MS instrumentation (i.e. DDA, DIA approaches using label-free or TMT quantification) • Proficiency in data processing with tools such as MetaboAnalyst, Skyline, MaxQuant, Proteome Discoverer, EncyclopeDIA or similar. • Mass spectrometry-based targeted quantitative lipid analyses or discovery lipidomics. Note: • 100% lab based role. Key skills to focus:- • Hands on Mass spectrometry assays expertise needed. • Developing quantitative assays using Mass spectrometry. • Proficiency with tools such as MetaboAnalyst, Skyline, MaxQuant, Proteome Discoverer, EncyclopeDIA or similar.