Site: The Brigham and Women's Hospital, Inc.


At Mass General Brigham, we know it takes a surprising range of talented professionals to advance our mission-from doctors, nurses, business people and tech experts, to dedicated researchers and systems analysts. As a not-for-profit organization, Mass General Brigham is committed to supporting patient care, research, teaching, and service to the community. We place great value on being a diverse, equitable and inclusive organization as we aim to reflect the diversity of the patients we serve.


At Mass General Brigham, we believe a diverse set of backgrounds and lived experiences makes us stronger by challenging our assumptions with new perspectives that can drive revolutionary discoveries in medical innovations in research and patient care. Therefore, we invite and welcome applicants from traditionally underrepresented groups in healthcare - people of color, people with disabilities, LGBTQ community, and/or gender expansive, first and second-generation immigrants, veterans, and people from different socioeconomic backgrounds - to apply.



Job Summary
The Division of Sleep and Circadian Disorders at Brigham and Women's Hospital and Harvard Medicine School is looking for a talented Biostatistician to join our laboratory within the Program in Sleep Medicine Epidemiology. The candidate would perform genetic and electronic health record-based analyses of sleep apnea and related comorbidities in humans. Data sources include the Mass General Brigham biobank and linked sleep clinic data, the UK and All of Us biobanks, and the Trans-Omics for Precision Medicine (TOPMed) consortium and linked cohort study sleep data. In these cohorts, data to be analyzed includes whole-genome and imputed genetic data, advanced polysomnographic sleep apnea phenotypes, and clinical diagnoses, laboratory results, and note phrases classified using natural language processing. Methods include genetic association, causal mediation and machine learning.


The work will be performed as part of an interdisciplinary team, consisting of geneticists and genetic epidemiologists, biostatisticians, computational biologists, and translational scientists and clinicians. Successful candidates will work closely with students, postdoctoral fellows, and faculty.



Qualifications



Principal duties and responsibilities:


• Perform statistical design, modeling, and analysis.
• Provide statistical summaries and reports of data analysis
• Consult with investigators to ensure proper use of statistical methodology and interpretation of results.
• Efficiently leverage local compute, public and private cloud.
• Oversee data processing, dissemination, and access to high-dimensional data.
• Provide statistical and analytic support.



QUALIFICATIONS:



MS in Computer Science, Bioinformatics, Biostatistics, or a related quantitative field. Formal coursework in a biological science required. Must have previous research experience in epidemiology, genetics, and/or biomarkers of human disease.



SKILLS/ ABILITIES/ COMPETENCIES REQUIRED:



• Experience in Programing with Python and R that focuses on computational biological applications within a Linux environment.


• Demonstrated ability as the lead author of scientific reports and/or manuscripts.


• Ability to work in a highly collaborative and intellectually challenging environment.


• Must work independently


• Excellent oral and written communication skills.



Additional Job Details (if applicable)


Additional Job Description



Remote Type


Onsite



Work Location


221 Longwood Avenue



Scheduled Weekly Hours


40



Employee Type


Regular



Work Shift


Day (United States of America)



EEO Statement:


The Brigham and Women's Hospital, Inc. is an Affirmative Action Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.



Mass General Brigham Competency Framework


At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.