Adherence to all Good Manufacturing Practices (GMP) Safety Standards, Laboratory Setting, Office, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.), Will work with hazardous/toxic materials
Job Description
Location/Division Specific Information
The Bend, Oregon Thermo Fisher Scientific site consists of approximately 90 highly motivated employees focused on contract early phase clinical drug product formulation development and manufacture. Our site falls within the Pharma Services Group (PSG), which also encompasses manufacture of drug substance, scale up, clinical distribution, and commercial drug product launch.
How will this position make an impact
An early development scientist will provide analytical support and guidance for pre-clinical and clinical development material and provide input for early formulation selection. Analytical support includes chemical and physical analysis for active ingredients, intermediates, and final products.
What will this position do
Work in a fast-paced environment performing testing typically amorphous dispersions and oral solid dosage forms using various analytical techniques, such as HPLC, Dissolution, GC, KF, XRPD, DSC, DVS, TGA.
Record and report results of analysis in accordance with prescribed lab procedures and systems.
Clearly and accurately communicate the results of work by creating documentation of the testing/analysis and obtained results to the internal team and external clients.
Review and analyze analytical test results, make recommendations for formulation selection and experimental design. Lead technical discussions with internal team and external clients.
Manage multiple project timelines, ensure result targets are met, delegate tasks to supporting scientists as needed.
Chip in to maintaining a clean and organized laboratory workspace consistent with management expectations.
Collaborate with internal scientific, analytical, and laboratory functional areas to meet project and team objectives.
Research current methodologies and assist with implementation of new methodologies and processes with supervisor support and approval.
Mentor scientists throughout the company.
Participate in building process improvements.
Perform all duties in strict compliance with Standard Operating Procedures, Good Manufacturing Practices, Good Laboratory Practices, and Safety guidelines.
How will you get here
Education: Bachelor of Science in Chemistry, Biochemistry, Biology, or related physical science preferred
Experience: 7+ years working in a laboratory environment preferred; 2+ years of HPLC experience performing assay/related substance analysis and other chromatographic or spectroscopic techniques preferred.
Extensive experience with Dissolution and other analytical techniques.
Experience with client communications.
Experience with small molecules, amorphous dispersions and oral solid doses preferred.
Equivalent combinations of education, training, and relevant work experience may be considered.
Knowledge, Skills, Abilities
Excellent knowledge and understanding of basic instrumental technologies.
Excellent knowledge of qualitative and quantitative chemical analysis.
Knowledge of Good Manufacturing Practices and data integrity (ALCOA).
Excellent critical and logical thinking skills.
Effective written, interpersonal, and presentation skills.
Ability to read, analyze, and interpret technical procedures.
Ability to apply mathematical operations to such tasks as determination of test reliability, analysis of variance, and correlation techniques.
Proficiency in Microsoft Office Suite (Word, Excel, and PowerPoint).
