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At AstraZeneca's Oncology R&D division, we follow the science to explore and innovate. We are working towards treating, preventing, modifying, and even curing some of the world's most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. We are committed to making a difference and have built our business around our passion for science. Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs.
Position Summary
The Scientist is responsible for supporting our efforts in developing TCR-based immunotherapies for solid tumors within the Translational Sciences group. Your work will support clinical biospecimen characterization for clinical sample processing. Your role will be a hands-on and based onsite in Santa Monica, CA and reporting into a Senior Scientist.
Responsibilities
Perform clinical biospecimen characterization, data analysis, and reporting of results in the form of presentations or written reports, following standard operating procedures (SOPs).
Perform timely and accurate peer data audits and monitor data quality, in compliance with in-house and regulatory standards across multiple clinical programs.
Support design and qualification of cell-based functional assays.
Document laboratory procedures and results accurately in an electronic laboratory notebook.
Review and/or author SOPs, qualification reports, and other documents.
Analyze, organize, and communicate results at different research and cross-functional meetings. Participate in project teams and work cross-functionally to ensure alignment.
Other duties as assigned.
Position requires working with biological and/or chemical hazards.
Education and Experience
Bachelor's with a minimum of 5 years or Master's with minimum of 2 years with a degree in immunology, cellular or tumor biology or in a relevant discipline with related lab or industry experience.
Background in immunology and/or immunotherapy is strongly preferred.
Well-versed in cell culture aseptic techniques, multi-color flow cytometry (10+ colors), PCR, MSD/ELISA, and/or other cellular assays. Experience with spectral flow cytometry is a plus.
Detail-oriented with strong organizational, record keeping, and problem-solving skills.
Excellent interpersonal, verbal, and written communication skills are essential in this collaborative work environment.
Comfortable in a fast-paced company environment and able to adjust workload based upon changing priorities.
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The annual base pay for this position ranges from $84,865 to $116,689. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program, Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
