Are you a visionary authority in translational science, with the ability to implement a successful strategy in accelerating the development of cellular therapies for patients with immune-mediated diseases? If you are passionate about transforming the treatment of immune-mediated diseases and making a profound impact on patients' lives, then AstraZeneca might be the place for you! Our ambition is to build an outstanding organization that accelerates the delivery of transformative cell therapies for patients with immune-mediated diseases. We are driven by courage, curiosity, and collaboration, making bold decisions driven by patient outcomes.
Accountabilities
As a Translational Science Associate Director, you will be responsible for the implementation of translational and biomarker objectives for cellular therapies for immune-mediated diseases. Your focus will be on ensuring effective collaborations between research and development, establishing strong target-to-disease connections, differentiating AZ cellular therapeutics, and driving translational understanding of clinical trial data. You will oversee translational studies and deliverables with CROs and collaborators to support new and ongoing clinical studies as well as to enable our LCM strategy. You will be recognized as an authority in translational science and work on difficult drug projects and complex scientific problems, providing solutions that are highly innovative.
Essential Skills/Experience
PhD or MD-PhD degree required. Degree or training in Immunology preferred.
3 or more years of industry or combined academic/industry experience in clinical development or translational science.
Strong knowledge of the pathogenesis of immune mediated disease and the application of cellular, molecular technologies and models to drive program decisions, including those related to supporting value propositions.
Experience in clinical biomarker development of T-cell therapy and/or other advanced therapeutic modalities.
Prior experience in BM, precision medicine, and IND filings.
Proven ability to learn new information rapidly and effectively.
Significant experience managing CROs for translational studies and biomarkers for clinical trials.
Experience in the authoring of relevant sections regulatory documents.
Understanding of the full drug development process.
Detailed understanding of translational and clinical research methodology and biostatistics principles.
Understanding of FDA, EMA, MHRA and ICH GCP guidelines.
Attention to detail, strive to generate high-quality work, and sense of passion and urgency to achieve team and program goals.
Demonstrated experience contributing to and leading complex projects.
Demonstrated track record in delivering results.
Outstanding verbal and written communication skills.
Excellent analytical, problem solving and strategic planning skills.
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and daring world.
At AstraZeneca, we are committed to making a difference by fusing data and technology with the latest scientific innovations to achieve breakthroughs. We celebrate our successes and learn from our failures as we push the boundaries of science to deliver life-changing medicines. Our inclusive environment encourages collaboration with academia, biotechs, and industry partners to create the greatest impact on disease. Here, you will find opportunities for lifelong learning and career development while working on pioneering approaches to healthcare.
Ready to make a difference? Apply now to join our team!
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
