Staff Scientist, Applied Science in Therapeutic Oligonucleotides at Integrated DNA Technologies (IDT)

Posted in Other 1 day ago.

Location: Waterloo, Iowa





Job Description:

Integrated DNA Technologies (IDT) is the leading manufacturer of custom oligonucleotides and proprietary technologies for genomics applications. Our work is complex and
cutting-edge
, and our team members are curious, creative thinkers who understand that good data drives smart decisions. At IDT, we realize that although science may be uniform, people are unique. We promote a culture where engaged people are motivated and have opportunities to achieve their full potential, as part of one global team.


IDT is one of 10 Life Sciences companies of Danaher. Together, we accelerate the discovery, development and delivery of solutions that safeguard and improve human health.


This position
is part of
the

Applied Sciences for Therapeutic Oligonucleotides team in our Gene Writing and Editing Business Unit



located
in

Coralville, Iowa

and will be

on-site

. At
IDT
,
we are one global team. We celebrate our differences, engage in healthy
debate
, and
are
inclusive. Together, we
accomplish

great things
!




In this role, you will have the opportunity to:



  • Function as the lead scientist driving and executing projects as part of
    IDT's new
    Genomics Medicine Service offerings related
    to:

    off-target safety assessment for CRISPR-based editing systems
    ,
    CRISPR
    guide RNA sequencing, and

    additional
    ,
    custom projects associated with IDT's Therapeutic Oligonucleotides business.




  • Provide leadership
    , training, planning, etc. related to

    all aspects of
    therapeutic oligonucleotides
    projects
    inclusive of lab work, project tracking
    and organization
    , data collection, data analysis, report generation, and data presentation




  • Demonstrate skill
    s
    as a technical expert integral to
    facilitating
    technology transfer of methods from R&D to the Gen Meds Services team; additionally, provide plans to execute further feasibility,
    development
    and validation of assays for broader use and application




  • Lead projects and lend subject matter
    expertise
    to customer-specific oligo assessment of quality, performance, safety, etc. in cell-based,
    biochemical
    or analytical assays; help to define technical and experimental work plans related to these efforts to advance customer projects while supporting
    customer
    progress towards cGMP oligonucleotide synthesis
    .






The essential requirements of the job include:





  • Bachelor's degree (in Biology, Genetics,
    Chemistry
    or a related life sciences field) with
    10+
    years relevant lab experience OR a
    Master's degree (in Biology, Genetics,
    Chemistry
    or a related life sciences field) with
    8+
    years relevant lab experience OR a
    PhD degree (in Biology, Genetics,
    Chemistry
    or a related life sciences field) with
    5+
    years relevant lab experience




  • Demonstrated experience and technical
    background in CRISPR and
    Gene Editing rooted in
    research
    ,
    development
    , or applications.




  • Demonstrated
    expertise
    in CRISPR-based editing technologies via
    peer-reviewed publication record or product development history.




  • Demonstrated
    expertise
    in cell culture techniques, delivery of genome editing components to various cell types, and management of good laboratory practices in a tissue culture lab
    .




  • Demonstrated
    s
    trong experience in next-generation sequencing technology development and/or application, including d
    emonstrated ability of critical thinking applied to experimental planning,
    data analysis and data presentation
    s






Travel, Motor Vehicle Record & Physical/Environment Requirements:



  • Ability to travel
    domestically and internationally

    approximately 10%







It would be a plus if you also
possess

previous
experience in:



  • Delivering results in a regulated space (GLP, ICH, cGMP, etc.).




  • Bioinformatics related to assessment of genome editing or working with bioinformatics experts towards NGS-based assessment of genome editing events




  • Operating under design control and design assurance in product development




  • Custom genomics product development,
    verification
    or validation






Join our winning team today. Together, we'll accelerate the real-life impact of tomorrow's science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life.




For more information, visit

www.danaher.com

.



Danaher Corporation and all Danaher Companies are committed to equal opportunity regardless of race, color, national origin, religion, sex, age, marital status, disability, veteran status, sexual orientation, gender identity, or other characteristics protected by law. We value diversity and the existence of similarities and differences, both visible and not, found in our workforce, workplace and throughout the markets we serve. Our associates, customers and shareholders contribute unique and different perspectives as a result of these diverse attributes.



The EEO posters are available here.



We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform crucial job functions, and to receive other benefits and privileges of employment. Please contact us at applyassistance@danaher.com to request accommodation.



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