Senior Research Investigator (Department of Pharmacology)
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Posted Job Title
Senior Research Investigator (Department of Pharmacology)
Job Profile Title
Research Investigator, Senior
Job Description Summary
The functions of this position will include: rapid and large scale production and development of nucleoside-modified mRNA, developing and performing all quality control analyses on all mRNAs produced in the lab, development of targeted lipid nanoparticle (LNP) formulations specifically for in vivo use, and performing all required quality controls, and most critically, developing new techniques to both large scale produce mRNA and targeted LNP. They will be required to develop their own assays and methods, troubleshoot these methods, and analyze the data to determine the next steps in development. They also need to lead research projects and train junior lab members
Job Description
Job Responsibilities
Develop targeted nucleoside-modified mRNA-LNP for various mRNA cargoes
Perform in vitro assays
Perform in vivo assays-mice and rats mainly
Maintain complete and accurate lab notes
Develop new methods to cGMP produce nucleoside-modified mRNA
Develop new methods to cGMP produce targeted lipid nanoparticles
Qualifications
Doctor of Philosophy or equivalent doctoral degree, and 5 to 7 years of postdoctoral experience is required. Must have extensive laboratory experience working with molecular biology techniques and mRNA. Must be willing to work with small laboratory animals. Prior experience with tissue culture work is preferred.
Position is contingent upon continued funding.
Job Location - City, State
Philadelphia, Pennsylvania
Department / School
Perelman School of Medicine
Pay Range
$43,888.00 - $94,753.00 Annual Rate Salary offers are made based on the candidate's qualifications, experience, skills, and education as they directly relate to the requirements of the position, as well as internal and market factors and grade profile.
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Special Requirements
Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.
University Benefits
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