Job Description: Oregon Health & Science University
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Senior Research Associate
US-OR-Portland
Job ID: 2024-32191 Type: Regular Full-Time # of Openings: 1 Category: Research Portland, OR (Marquam Hill)
Overview
Molecular biological studies on Leishmania parasites, including tagging of genes with various epitopes, knocking out genes, generating various recombinant DNA constructs for mapping of regions of protein involved in trafficking, etc.
Protein-protein interaction studies to identify proteins that are critical for targeting of membrane proteins to the Leishmania flagellum.
Cell biological studies to localize proteins within the parasite and to study the mechanism of their trafficking to the parasite flagellum.
Studies with murine models of Leishmania infection to determine the effects of various gene knockouts on the ability of the parasite to infect a mammalian host.
Analysis of data from each of the above types of experiments.
Responsibilities
PhD in relevant field AND 1 year of relevant experience OR
Master's Degree in relevant field AND 5 years of relevant experience OR
Bachelor's Degree in relevant field AND 9 years of relevant experience
Previous work with molecular and cellular biology
Working with recombinant DNA, assembling recombinant constructs, transfection of constructs into cells, experience with CRISPR/Cas9 methods of gene editing in parasites, microscopic analysis
Qualifications
Some additional postdoctoral experience in the field