Job Description:

Department:

Marsico Lung Inst - CF Center - 426401

Posting Open Date:

10/16/2024

Application Deadline:

11/18/2024

Open Until Filled:

No

Position Type:

Postdoctoral Scholar

Position Title:

Postdoctoral Trainee

Vacancy ID:

PDS004358

Full-time/Part-time:

Full-Time Temporary

Hours per week:

40

FTE:

1

Work Location:

Chapel Hill, NC

Position Location:

North Carolina, US

Hiring Range:

Dependent upon qualifications, experience and NIH Market rates

Proposed Start Date:

12/01/2024

Estimated Duration of Appointment:

12 Months

Be a Tar Heel!:

A global higher education leader in innovative teaching, research and public service, the
University of North Carolina at Chapel Hill consistently ranks as
one of the nation's top public universities and is among is the top ten research universities in the nation for federal research expenditures as well as for federally funded social and behavioral sciences research and development.Here at Carolina, our highly skilled postdocs play a vital role in our research enterprise and towards our overall commitment to research excellence. Across many disciplines, postdocs contribute to the intellectual vitality of the University. They provide innovative ideas and perspectives, foster a stimulating research environment and advance knowledge within their fields. Postdocs are crucial members of our scientific research workforce, contributors to our research outputs and an important reason why Carolina is one of the leading public research institutions in the country.UNC-Chapel Hill offers postdocs comprehensive
medical and vision coverage, paid leave, and
benefits and services that support professional development and a healthy work/life balance. Chapel Hill regularly ranks as one of the best college towns and best places to live in the United States, a reputation guided by the diverse social, cultural, recreation and professional opportunities that span the campus and community.

Primary Purpose of Organizational Unit:

The UNC School of Medicine has a rich tradition of excellence and care. Our mission is to improve the health and wellbeing of North Carolinians, and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education, and research. We strive to promote faculty, staff, and learner development in a diverse, respectful environment where our colleagues demonstrate professionalism, enhance learning, and create personal and professional sustainability. We optimize our partnership with the UNC Health System through close collaboration and commitment to service.The goal of the Marsico Lung Institute and the Cystic Fibrosis/Pulmonary Research and Treatment Center is to provide the mechanism for generating world-class research into the pathogenesis and treatment of diseases that impact on the human lung. Basic research activities focus on the elucidation of the pathogenesis of human lung diseases at the molecular, biologic, cell biologic and physiologic levels. Clinical and therapeutic studies focus on specific disease categories, exploring pathophysiologic concepts in patients with these diseases, and, with the collaboration of basic and clinical investigators, developing rational, novel ways for treatment of lung diseases.

Position Summary:

This Postdoctoral Trainee position is available through a NIH T32 training program, designed to train promising early career investigators. The Postdoctoral Trainee will investigate the kinetics and function of neutrophils and macrophage subpopulations in developing and resolving pneumonia. One active focus is on the expression and function of ICAM-1 on alveolar epithelial cells, endothelial cells and immune cells. Studies also focus on neutrophil heterogeneity, its regulation and function. Studying these processes in acute lung injury and in injury caused by inhalation of toxicants is also a component of this position. The studies utilize molecular and cell biological technologies including single cell RNAseq/CITEseq, bulk RNA profiling and qPCR, cell culture, flow cytometry, mass cytometry, cell sorting, ELISAs, immunoblotting, murine experimentation, and histology, as well as translational science technologies.


Essential duties of the Postdoctoral Trainee include:· Designing and carrying out studies;· Analyzing and interpreting data;· Publishing papers describing these results, all with the mentor.


Career development of the Postdoctoral Trainee will be an important component of this position.

Minimum Education and Experience Requirements:

A PhD in Immunology, Pathology, Genetics, Cell and Molecular Physiology or similar discipline required and/or MD.

Required Qualifications, Competencies, and Experience:

Experience in Immunology, Pathology, Genetics, Cell and Molecular Physiology or similar discipline are required.

Preferred Qualifications, Competencies, and Experience:

Preferred qualifications include:
1) Coursework or knowledge in immunology (particularly inflammation and innate immunity), cell and molecular physiology, and/or pathology of disease,
2) Experience and proficiency in some of the technologies described above, and
3) Experience in mouse models of lung disease.

Special Physical/Mental Requirements :

N/A

Special Instructions:

For information on UNC Postdoctoral Benefits and Services
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