Description: Postdoctoral or more senior research positions are available in the Ludwig Princeton Branch to study metabolism and tumor-microenvironment interactions during cancer progression. Ludwig Princeton Branch is dedicated to accelerating the study of metabolic phenomena associated with cancer to develop new paradigms for cancer prevention and treatment. Its main research areas include: - Metabolic interactions between the tumor and the rest of the body, focusing on how the body supports tumor growth and metastasis, and how tumors induce cachexia and other microenvironmental changes. - Interplay between host metabolism, gut microbiome, and anti-cancer immune response. - Diet-induced tumor microenvironment changes during cancer progression and metastasis, and dietary strategies for the prevention and treatment of cancer. We welcome highly motivated candidates who have or expect to have a Ph.D. degree in the fields of molecular cell biology, cancer biology, chemical biology, biochemistry, cancer genomics, genetics, mass spectrometry, physical chemistry, computational and systems analysis. The term of appointment is based on rank. Positions at the postdoctoral rank are for one year with the possibility of renewal pending satisfactory performance and continued funding; those hired at more senior ranks may have multi-year appointments. Applicants must select one or more research mentor/co-mentor from the following Principal Investigators and Ludwig Princeton Branch members. Please visit https://ludwigcancer.princeton.edu/ to learn more about each Principal Investigator Rabinowitz, Joshua - Major areas of interest include: Metabolomics, isotope tracing, metabolic flux analysis, quantitative modeling, mass spectrometry imaging, cancer metabolism, small molecule inhibitor discovery, dietary impact on cancer, metabolism, and the immune system. White, Eileen- Major areas of interest include: Identification of metabolic vulnerabilities in cancer, the role of nutrient scavenging pathways including autophagy in cancer and host metabolism, growth and survival, metabolic control of the anti-tumor immune response, identification of the mechanisms driving cancer cachexia, dietary modulation of tumor growth and treatment response. Kang, Yibin - Major areas of interest include: Cellular plasticity in cancer progression, organ-tropic metastasis niches, metabolic adaptation during cancer metastasis, metastasis genes and development of metastasis therapeutics, mammary gland stem cell and stem cell niches. Lynch, Lydia - Major areas of interest include: Whole-body metabolism and its impact on the immune system and cancer. Skinnider, Michael - Major areas of interest include: Illuminating metabolic dark matter by developing new computational approaches to identify both known and unknown small molecules using mass spectrometry. To apply for a position in the Skinnider lab, please visit https://www.princeton.edu/acad-positions/position/35542. To apply online, please visit https://puwebp.princeton.edu/AcadHire/position/36962 and submit a brief statement of research interests, curriculum vitae and a list of three references. This position is subject to the University's background check policy. The work location for this position is in-person on campus at Princeton University.
