Senior Scientist, Bioscience Immunology, Early Respiratory And Immunology



Are you passionate about science and eager to apply your expertise in a company that follows the science and turns ideas into life-changing medicines? If so, AstraZeneca might be the one for you! We are seeking an experienced and highly motivated researcher with a strong understanding of adaptive and/or innate immunity. This role will be based in Waltham, MA (Boston BioHub) within AstraZeneca's innovative laboratories where you will follow the science to help drive innovation and advance medicines. This position offers a unique opportunity to work in a dynamic and innovative environment developing your career at the interface of mechanistic research, drug discovery and preclinical drug development.



Accountabilities:



In this role, you will be a biology leader in the Bioscience, Immunology team focusing on developing therapeutics for treatment of Rheumatological and Gastrointestinal Diseases. You will contribute to the development of new target identification strategies, characterization of immunological pathways in health and disease and drive the development of novel drug candidates. You will also work closely with key leaders in partner functions to ensure project goals are met and create and maintain a productive and collaborative work environment.



Essential Skills/Experience:



- Relevant degree in immunology, or a relevant discipline: Ph.D. with 3+ years of experience (preferentially in pharma/biotech) OR MS with 6+ years of experience, or BS degree with 10+ years and project leadership experience in a relevant field.


- Deep knowledge of adaptive and/or innate immune cell biology is critical, preferentially with strong hands-on experience with human T cells. Treg or CAR-Treg experience is a bonus.


- Expertise in drug discovery projects in the immunology, fibrotic diseases or a closely related field of biology is preferred.


- Expertise in primary human cell culture, multi-color flow cytometry, multiplex cytokine detection and functional assays (proliferation, cytotoxicity, chemotaxis...) and assay development is essential.


- Strong hands-on skills in molecular biology are a plus.


- Initiative to identify and leverage internal and external resources to advance drug discovery efforts.


- Demonstrated ability to work in a dynamic environment, record protocols and experiments detailed and in a timely manner and maintain an excellent laboratory notebook.


- Strong written and oral communication skills and the ability to critically analyze datasets are essential.



Desirable Skills/Experience:



- Experience with 3D in vitro models and in vivo models is a bonus.


When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.



Why AstraZeneca?



As Clinical Development Physicians and Scientists in Oncology, we push the boundaries of science to change the practice of medicine and transform the lives of patients living with cancer. With one of the broadest and deepest Oncology pipelines in the industry, there are many opportunities to work with new and novel drugs and help discover what's next. We foster a mindset of courage, where everyone is empowered to step up, innovate and work at pace. Our pipeline is a testament to our growth, both now and in the future.



Are you ready to make a difference? Apply today and join us in our mission to eliminate cancer as a cause of death!



AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.