Adherence to all Good Manufacturing Practices (GMP) Safety Standards, Office, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.)
Job Description
How will you make an impact?
Next Generation Sequencing (NGS) is rapidly reshaping life sciences, translational research, and clinical diagnostics. At Thermo Fisher Scientific, a leading contributor in these fields, we are dedicated to broaden the range of NGS applications with a focus on comprehensive oncology diagnostics. If you are a motivated and innovative scientist seeking to advance your expertise in these fields, we would like to invite you to join our NGS R&D team. The candidate will have strong experimental skills, a broad understanding of molecular biology, and an understanding of regulated product development (CE-IVD and IVD).
What will you do?
You will:
Design and perform experiments to improve and develop nucleic acid purification reagents and automated workflows for variety of sample types including Whole blood, Plasma, FFPE and Urine.
Perform laboratory bench work with focus on sample preparation and sequencing to support development of targeted sequencing assays.
Perform various studies through analytical validation and clinical validation phases of product development.
Perform experimental design, basic data analysis, interpretation, and data summarization to help guide product development.
Prioritize daily activities to ensure timely completion of tasks and projects.
Work in close collaboration with cross functional teams including bioinformatics, engineering, Product Managment, Manufacturing, and Regulatory affairs to deliver high quality results.
Maintain accurate and detailed lab notebooks and appropriate documentation
Support On-Market product and manufacturing troubleshooting with strong "customer-first" mind set.
Follow ISO 9001 and 13485 requirements.
How will you get here?
Education
MS/PhD in Biology/Molecular Biology or related field with minimum 2 years relevant experience or BS with minimum 3-5 years relevant experience
Experience
Possess a clear understanding and have related experience in basic chemistry and molecular biology techniques (including Nucleic acid extractions, quantitation and characterization, PCR techniques, and Reagent/buffer preparation)
You should have a solid knowledge of the next-generation sequencing as demonstrated by your publication history or industry experience.
In depth understanding of genomics and cancer biology will make you a stronger candidate.
Experience in IVD product development is a plus.
Experience in automated nucleic acid purification platforms such as Genexus, KingFisher or similar, and Liquid handers is a plus.
Effective communication skills, especially for presenting scientific results, keeping records and working collaboratively in a team of scientists are necessary.
Must have the ability to take initiatives and operate with minimal supervision.
