Zoetis Veterinary Medicine Research and Development, Biologics Analytical Sciences in Lincoln, NE is seeking a scientist at the Scientist/Senior Scientist level. The successful candidate will work with other analytical to execute analytical testing in support of biopharmaceutical and/or vaccine product development. The incumbent will also be responsible for analytical method development, validation, and transfer exercises as appropriate. The candidate in this position will work collaboratively with multi-disciplinary teams (analytical, bioprocess, clinical) and support multiple projects in development.
Responsibilities include, but are not limited to, the following:
Design and conduct laboratory experiments including analytical method development, validation and transfer. Primary techniques are mass spectrometry (LC-MS and LC-MS/MS), HPLC, immunoaffinity based separations/extractions/assays, electrophoresis, spectrophotometric assays, and microplate-based assays.
Execute analyses of peptides and proteins using different types of mass spectrometers (e.g. single quadrupole, triple quadrupole, quadrupole time-of-flight).
Perform characterization of peptides and protein PTMs such as disulfide bonds, methionine oxidation, deamidation, etc. using mass spectrometry.
Perform analytical methods necessary for the development and characterization of proteins and peptides in vaccines and therapeutic formulations.
Document and communicate results in laboratory notebooks, technical reports, and oral presentations.
Collaborate with other scientists in a variety of technical disciplines including within Analytical Sciences, Process Development, Biological Research, Regulatory, Quality Control and Manufacturing.
Minimum Qualifications:
Degree in Biochemistry, Chemistry, or a related field.
BS with 5+ years of experience, MS with 4+ years of experience, or PhD with 0+ years of experience.
Good oral and written communication skills.
Preferred Qualifications:
More than two years of industry experience in developing, validating, and transferring biopharmaceutical and/or vaccine analytical methods.
Experience in analytical method development utilizing techniques such as HPLC, electrophoresis, and/or mass spectrometry.
Knowledge of regulatory requirements associated with USDA and EU biologics submissions.
Knowledge of GxPs, including analytical method validation and transfer.
Skills and experience in experimental design, technical problem solving, and continuous improvement.
Full time
Regular
Colleague
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